In a large bowl, whisk together eggs, milk, pumpkin puree, pumpkin pie spice, vanilla, and salt.
Melt 1/2 tablespoon butter in a large skillet over medium heat.
Working in batches, dip bread slices into the egg mixture until lightly coated, then add to skillet with melted butter. Cook slices, 1-2 at a time, until evenly golden brown, about 2 minutes on each side. Repeat with remaining bread and butter.
Serve Pumpkin Spice French Toast with maple syrup and confectioners’ sugar, if desired.